what happens to pyruvic acid in aerobic respiration

v.3B: Pyruvic Acrid and Metabolism

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Learning Objectives

Outline the metabolic processes that involve pyruvate

Pyruvic acid (CH₃COCOOH; is an organic acid, a ketone, and the simplest of the alpha-keto acids. The carboxylate (COO⁻) anion of pyruvic acid. The Brønsted–Lowry conjugate base, CH₃COCOO⁻, is known as pyruvate, and is a central intersection in several metabolic pathways.

Figure: **Pyruvic acid**: Pyruvic acid can exist made from glucose through glycolysis, converted back to carbohydrates (such as glucose) via gluconeogenesis, or to fatty acids through acetyl-CoA. It can as well be used to construct the amino acrid alanine and be converted into ethanol. Pyruvic acrid supplies energy to living cells through the citric acid cycle (also known as the Krebs wheel) when oxygen is present (aerobic respiration), and alternatively ferments to produce lactic acrid when oxygen is lacking (fermentation).

Pyruvic acid can be made from glucose through glycolysis, converted back to carbohydrates (such as glucose) via gluconeogenesis, or to fatty acids through acetyl-CoA. It can as well be used to construct the amino acrid alanine, and it can be converted into ethanol.

Pyruvic acid supplies free energy to living cells through the citric acrid cycle (besides known as the Krebs cycle) when oxygen is nowadays (aerobic respiration); when oxygen is defective, it ferments to produce lactic acrid. Pyruvate is an important chemical compound in biochemistry. It is the output of the anaerobic metabolism of glucose known as glycolysis. One molecule of glucose breaks downwardly into 2 molecules of pyruvate, which are then used to provide farther energy in one of two ways. Pyruvate is converted into acetyl- coenzyme A, which is the chief input for a series of reactions known as the Krebs wheel. Pyruvate is also converted to oxaloacetate by an anaplerotic reaction, which replenishes Krebs bicycle intermediates; also, oxaloacetate is used for gluconeogenesis. These reactions are named after Hans Adolf Krebs, the biochemist awarded the 1953 Nobel Prize for physiology, jointly with Fritz Lipmann, for enquiry into metabolic processes. The cycle is likewise known equally the citric acid wheel or tri-carboxylic acid cycle, considering citric acid is 1 of the intermediate compounds formed during the reactions.

If insufficient oxygen is available, the acid is cleaved down anaerobically, creating lactate in animals and ethanol in plants and microorganisms. Pyruvate from glycolysis is converted by fermentation to lactate using the enzyme lactate dehydrogenase and the coenzyme NADH in lactate fermentation. Alternatively information technology is converted to acetaldehyde then to ethanol in alcoholic fermentation.

Pyruvate is a key intersection in the network of metabolic pathways. Pyruvate can be converted into carbohydrates via gluconeogenesis, to fatty acids or energy through acetyl-CoA, to the amino acrid alanine, and to ethanol. Therefore, information technology unites several key metabolic processes.

Central Points

Pyruvic acid tin be made from glucose through glycolysis, converted back to carbohydrates (such as glucose) via gluconeogenesis, or to fatty acids through acetyl-CoA.
Pyruvic acid supplies energy to living cells through the citric acrid cycle (also known as the Krebs cycle ) when oxygen is present (aerobic respiration); it ferments to produce lactic acid when oxygen is lacking ( fermentation ).
Pyruvate is the output of the anaerobic metabolism of glucose known as glycolysis.
Pyruvate tin be converted into carbohydrates via gluconeogenesis, to fat acids or energy through acetyl-CoA, to the amino acid alanine, and to ethanol.

Key Terms

pyruvic acid: A colourless liquid; an of import intermediate in the metabolism of proteins and carbohydrates, and in fermentation.
cohabit base: Any chemical compound, of general formula Xn+, which can exist transformed into a conjugate acid HX(northward+ane)+ by the gain of a proton.
Krebs cycle: A serial of enzymatic reactions that occurs in all aerobic organisms; it involves the oxidative metabolism of acetyl units and serves as the chief source of cellular free energy.

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Source: https://bio.libretexts.org/Bookshelves/Microbiology/Book%3A_Microbiology_(Boundless)/5%3A_Microbial_Metabolism/5.03%3A_Catabolism/5.3B%3A_Pyruvic_Acid_and_Metabolism

what happens to pyruvic acid in aerobic respiration

v.3B: Pyruvic Acrid and Metabolism

Central Points

Key Terms

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